TENERIFE, Canary Islands — The first plane carrying passengers from the hantavirus-hit cruise ship left Spain’s Canary Islands on Sunday for Madrid, where they will be taken to a military hospital.

Spanish nationals were the first to leave the MV Hondius, which remains anchored off Tenerife, the largest island in the Spanish archipelago off the coast of West Africa. The ship arrived hours earlier.

None of the more than 140 people on the Hondius has shown symptoms of the virus, Spain’s health ministry, the World Health Organization and cruise company Oceanwide Expeditions said.

Those disembarking and personnel working at the port of Granadilla in Tenerife were wearing protective gear during the evacuation process, including face masks, hazmat suits and respirators.

“The entire operation is proceeding normally,” Spanish Health Minister Mónica García said.

Passengers and some crew members from more than 20 nationalities on board will be evacuated throughout Sunday into Monday.

After reaching Madrid, those evacuated on the first plane will be under quarantine, Spanish health authorities say. Only the 14 Spanish nationals on board will quarantine in the country.

Authorities have said the passengers and crew members disembarking will be checked for symptoms, have no contact with the local population and will only be taken off the ship once evacuation flights are ready to fly them to their destinations. WHO Director-General Tedros Adhanom Ghebreyesus and Spain’s health and interior ministers are supervising the operation in Tenerife.

Pope Leo XIV thanked the Canary Islands for allowing the arrival of the Hondius.

“I would like to thank the people of the Canary Islands who, with the hospitality characteristic of them, welcomed the cruise ship Hondius and the passengers infected with the Hantavirus. I look forward to seeing all of you next month during my visit to the Islands,” he said during is Regina Coeli address at the Vatican on Sunday.

Hantavirus usually spreads when people inhale contaminated residue of rodent droppings and isn’t easily transmitted between people. But the Andes virus detected in the cruise ship outbreak may be able to spread between people in rare cases. Symptoms usually show between one and eight weeks after exposure.

Three people have died since the outbreak, and five passengers who left the ship are infected with hantavirus, which can cause life-threatening illness.

Passengers and crew members disembarking are leaving behind their luggage, and are allowed to take only a small bag with essential items, a cellphone, a charger, and documentation.

Some crew, as well as the body of a passenger who died on board, will remain on the ship, which will sail on to Rotterdam, Netherlands, where it will undergo disinfection, Spanish authorities said.

The expected sailing time to Rotterdam is around five days, the cruise company said.

Evacuation and quarantine plans

The U.S., the United Kingdom and the Netherlands will send planes to evacuate their citizens. Americans on board will be quarantined at a medical center in Nebraska.

Twenty-nine people will be on board the Dutch charter flight, including Dutch nationals and people of other nationalities, the Dutch Foreign Ministry said.

Five French passengers will be repatriated Sunday, and will be hospitalized for 72 hours for monitoring, after which they will quarantine at home for 45 days, France’s Foreign Ministry said.

U.K. passengers and crew will be hospitalized for observation once they are flown home, British authorities say.

Australia is sending a plane, expected to arrive on Monday, to evacuate its nationals and those from nearby countries such as New Zealand, García said. Its plane will be the last to leave Tenerife, she said.

Norway has sent an ambulance plane to Tenerife with personnel trained to transport patients with high-risk infections, its Directorate for Civil Protection told public broadcaster NRK.

The ambulance plane is owned by the European Union, but operated by Norway.

Countries monitor suspected cases

British Army medics have parachuted onto the remote South Atlantic territory of Tristan da Cunha, where one of the 221 residents has a suspected case of hantavirus.

The patient was a passenger on the MV Hondius and disembarked last month.

The U.K. defense ministry says a team of six paratroopers and two medical clinicians jumped Saturday from a Royal Air Force transport plane, which also dropped oxygen and medical equipment.

Tristan da Cunha is Britain’s most remote inhabited overseas territory, about 1,500 miles (2,400 kilometers) from the nearest inhabited island, St. Helena. The group of volcanic islands has no airstrip and is usually accessible only by boat on a six-day voyage from Cape Town, South Africa.

Meanwhile, a Spanish woman in the southeastern province of Alicante suspected of being infected tested negative for hantavirus, Spanish health authorities said Saturday.

The woman was a passenger on the same flight as the Dutch woman who died in Johannesburg after traveling on the cruise ship.

Suman Naishadham reported from Madrid. Angela Charlton in Paris, Jill Lawless in London, and Kirsten Grieshaber in Berlin contributed to this report. Crux Now Staff contributed to this report.